Ganoderma Formosanum Gourmet Mushroom Culture

Sale!

$14.95

Your order today will contain:

(1) Sterile 12 ml syringe with locking cap, filled with fresh Ganoderma Formosanum Gourmet Mushroom  mycelium. 

(1) Mylar syringe sleeve for long-term storage.

(2) Alcohol pads.

(1) 16-gauge needle.

(1) Cold / Warm Weather insert (depending on shipping location and time of year)

(1) Free 20-gram sample pack of my mushroom nutrient broth premix.

A $15 value, make 1 liter of your own lab-quality mushroom liquid culture.

Description

Ganoderma Formosanum
Ganoderma Formosanum

The fungus of Ganoderma is a basidiomycete that possesses a variety of pharmacological effects and has been used in traditional Asian medicine for centuries. Ganoderma formosanum is a native Ganoderma species isolated in Taiwan, and we have previously demonstrated that PS-F2, a polysaccharide fraction purified from the submerged culture broth of G. formosanum, exhibits immunostimulatory properties in macrophages. In this study, we further characterized the adjuvant functions of PS-F2. In vitro, PS-F2 stimulated dendritic cells (DCs) to produce proinflammatory cytokines, including TNF-α, interleukin (IL)-6, and IL-12/IL-23 p40. PS-F2 also stimulated DCs to express the maturation markers CD40, CD80, CD86, and MHC class II. In a murine splenocyte culture, PS-F2 treatment resulted in elevated expression of T-bet and interferon (IFN)-γ in T lymphocytes. When used as an adjuvant in vivo with the ovalbumin (OVA) antigen, PS-F2 stimulated OVA-specific antibody production and primed IFN-γ production in OVA-specific T lymphocytes. PS-F2-adjuvated immunization also induced OVA-specific CTLs, which protected mice from a challenge with tumor cells expressing OVA. Collectively, our data show that PS-F2 functions as an adjuvant capable of inducing a Th1-polarized adaptive immune response, which would be useful in vaccines against viruses and tumors.

Additional information

Weight 1 oz
Dimensions 9 × 6 × 1 in

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